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1

Site-specific antibody drug conjugates for cancer therapy

Panowski, Siler, Bhakta, Sunil, Raab, Helga, Polakis, Paul, Junutula, Jagath R

Journal:

Year:

2014

Language:

english

File:

PDF, 2.32 MB

english, 2014

2

Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma

Laura A Strickland, Jed Ross, Simon Williams, Sarajane Ross, Maria Romero, Susan Spencer, Rich Erickson, Julie Sutcliffe, Caroline Verbeke, Paul Polakis, Nicholas van Bruggen, Hartmut Koeppen

Journal:

The Journal of Pathology

Year:

2009

Language:

english

File:

PDF, 600 KB

english, 2009

3

Identification and immunotherapeutic targeting of antigens induced by chemotherapy

Rubinfeld, Bonnee, Upadhyay, Archana, Clark, Suzanna L, Fong, Sharon E, Smith, Victoria, Koeppen, Hartmut, Ross, Sarajane, Polakis, Paul

Journal:

Nature Biotechnology

Year:

2006

Language:

english

File:

PDF, 374 KB

english, 2006

4

Induction of a β-catenin-LEF-1 complex by wnt-1 and transforming mutants of β-catenin

Waterman, Marian, Polakis, Paul, Porfiri, Emilio, Rubinfeld, Bonnee, Albert, Iris, Hovanes, Karine

Journal:

Year:

1997

Language:

english

File:

PDF, 210 KB

english, 1997

5

The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors

Crawford, Howard C, Fingleton, Barbara M, Rudolph-Owen, Laura A, Goss, Kathleen J Heppner, Rubinfeld, Bonnee, Polakis, Paul, Matrisian, Lynn M

Journal:

Year:

1999

Language:

english

File:

PDF, 535 KB

english, 1999

6

A Role for Hath1, a bHLH Transcription Factor, in Colon Adenocarcinoma

CHING CHING LEOW, PAUL POLAKIS, WEI-QIANG GAO

Journal:

Annals of the New York Academy of Sciences

Year:

2005

Language:

english

File:

PDF, 2.05 MB

english, 2005

7

Structural basis of the Axin–adenomatous polyposis coli interaction

Spink, Katharine Eklof, Polakis, Paul, Weis, William I

Journal:

The EMBO Journal

Year:

2000

Language:

english

File:

PDF, 1.07 MB

english, 2000

8

Drugging Wnt signalling in cancer

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 488 KB

english, 2012

9

The adenomatous polyposis coli (APC) tumor suppressor

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

1997

Language:

english

File:

PDF, 560 KB

english, 1997

10

Casein Kinase 1: A Wnt'er of Disconnect

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 48 KB

english, 2002

11

Downregulation of β-catenin by human Axin and its association with the APC tumor suppressor, β-catenin and GSK3β

Matthew J. Hart, Rico de los Santos, Iris N. Albert, Bonnee Rubinfeld, Paul Polakis

Journal:

Current Biology

Year:

1998

Language:

english

File:

PDF, 226 KB

english, 1998

12

A synthetic peptide corresponding to a sequence in the GTPase activating protein inhibits p21ras stimulation and promotes guanine nucleotide exchange

BONNEE RUBINFELD, GAIL WONG, EVA BEKESI, ALEXANDER WOOD, EDGAR HEIMER, FRANK McCORMICK, PAUL POLAKIS

Journal:

Chemical Biology & Drug Design

Year:

1991

Language:

english

File:

PDF, 632 KB

english, 1991

13

Proteolytic dissection of rat brain hexokinase: Determination of the cleavage pattern during limited digestion with trypsin

Paul G. Polakis, John E. Wilson

Journal:

Archives of Biochemistry and Biophysics

Year:

1984

Language:

english

File:

PDF, 6.78 MB

english, 1984

14

An intact hydrophobic N-terminal sequence is critical for binding of rat brain hexokinase to mitochondria

Paul G. Polakis, John E. Wilson

Journal:

Archives of Biochemistry and Biophysics

Year:

1985

Language:

english

File:

PDF, 1.47 MB

english, 1985

15

Purification of highly bindable rat brain hexokinase by High Performance Liquid Chromatography (HPLC)

Paul G. Polakis, John E. Wilson

Journal:

Biochemical and Biophysical Research Communications

Year:

1982

Language:

english

File:

PDF, 366 KB

english, 1982

16

Characterization of G25K, a GTP-binding protein containing a novel putative nucleotide binding domain

Paul G. Polakis, Ralph Snyderman, Tony Evans

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 2.06 MB

english, 1989

17

Multiple chromatographic forms of the formylpeptide chemoattractant receptor and their relationship to GTP-binding proteins

Paul G. Polakis, Tony Evans, Ralph Snyderman

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 1.86 MB

english, 1989

18

Regulation of the GTPase activity of the ras-related rap2 protein

Isabelle Janoueix-Lerosey, Paul Polakis, Armand Tavitian, Jean de Gunzburg

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1.27 MB

english, 1992

19

Arming antibodies for cancer therapy

Journal:

Current Opinion in Pharmacology

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

20

The many ways of Wnt in cancer

Journal:

Current Opinion in Genetics & Development

Year:

2007

Language:

english

File:

PDF, 257 KB

english, 2007

21

A blockade in Wnt signaling is activated following the differentiation of F9 teratocarcinoma cells

Sayumi Shibamoto, Jane Winer, Mickey Williams, Paul Polakis

Journal:

Experimental Cell Research

Year:

2004

Language:

english

File:

PDF, 394 KB

english, 2004

22

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of Axin and β-catenin

Gareth M. Thomas, Sheelagh Frame, Michel Goedert, Inke Nathke, Paul Polakis, Philip Cohen

Journal:

Year:

1999

Language:

english

File:

PDF, 248 KB

english, 1999

23

The Human p62 cDNA Encodes Sam68 and Not the RasGAP-Associated p62 Protein

Peter Lock, Stefano Fumagalli, Paul Polakis, Frank McCormick, Sara A. Courtneidge

Journal:

Year:

1996

Language:

english

File:

PDF, 80 KB

english, 1996

24

More Than One Way to Skin a Catenin

Journal:

Year:

2001

Language:

english

File:

PDF, 84 KB

english, 2001

25

Mutations in the APC gene and their implications for protein structure and function

Journal:

Current Opinion in Genetics & Development

Year:

1995

Language:

english

File:

PDF, 1.43 MB

english, 1995

26

The oncogenic activation of β-catenin

Journal:

Current Opinion in Genetics & Development

Year:

1999

Language:

english

File:

PDF, 103 KB

english, 1999

27

Evidence for SH3 domain directed binding and phosphorylation of Sam68 by Src

Shen, Zhiwei, Batzer, Andreas, Koehler, Jackie A, Polakis, Paul, Schlessinger, Joseph, Lydon, Nicholas B, Moran, Michael F

Journal:

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

28

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

Bonnee Rubinfeld, Susan Munemitsu, Robin Clark, Leah Conroy, Kenneth Watt, Walter J. Crosier, Frank McCormick, Paul Polakis

Journal:

Year:

1991

Language:

english

File:

PDF, 3.00 MB

english, 1991

29

Molecular cloning and nucleic acid binding properties of the GAP-associated tyrosine phosphoprotein p62

Gail Wong, Oliver Müller, Robin Clark, Leah Conroy, Michael F. Moran, Paul Polakis, Frank McCormick

Journal:

Year:

1992

Language:

english

File:

PDF, 1.66 MB

english, 1992

30

A Drosophila Homolog of the Tumor Suppressor Gene Adenomatous Polyposis Coli Down-Regulates β -catenin but its Zygotic Expression is not Essential for the Regulation of Armadillo

Shigemi Hayashi, Bonnee Rubinfeld, Brian Souza, Paul Polakis, Eric Wieschaus and Arnold J. Levine

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.66 MB

english, 1997

31

Adenomatous Polyposis Coli Tumor Suppressor Protein Has Signaling Activity in Xenopus laevis Embryos Resulting in the Induction of an Ectopic Dorsoanterior Axis

Kris Vleminckx, Ellen Wong, Kathy Guger, Bonnee Rubinfeld, Paul Polakis and Barry M. Gumbiner

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 2.15 MB

english, 1997

32

The Adenomatous Polyposis Coli Tumor Suppressor Protein Localizes to Plasma Membrane Sites Involved in Active Cell Migration

Inke S. Näthke, Cynthia L. Adams, Paul Polakis, Joseph H. Sellin and W. James Nelson

Journal:

The Journal of Cell Biology

Year:

1996

Language:

english

File:

PDF, 5.56 MB

english, 1996

33

Formation of the Blood-Brain Barrier: Wnt Signaling Seals the Deal

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 838 KB

english, 2008

34

An improved and robust DNA immunization method to develop antibodies against extra-cellular loops of multi-transmembrane proteins

Hazen, Meredith, Bhakta, Sunil, Vij, Rajesh, Randle, Steven, Kallop, Dara, Chiang, Vicki, Hötzel, Isidro, Jaiswal, Bijay S, Ervin, Karen E, Li, Bing, Weimer, Robby M, Polakis, Paul, Scheller, Richard

Journal:

Year:

2014

Language:

english

File:

PDF, 2.96 MB

english, 2014

35

Purification of a Plasma Membrane-Associated GTPase-Activating Protein Specific for Rap1/Krev-1 from HL60 Cells

Paul G. Polakis, Bonnee Rubinfeld, Tony Evans and Frank McCormick

Journal:

Proceedings of the National Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.04 MB

english, 1991

36

Drugging Wnt signalling in cancer

Journal:

The EMBO Journal

Year:

2012

Language:

english

File:

PDF, 38 KB

english, 2012

37

Regulation of Intracellular β-Catenin Levels by the Adenomatous Polyposis Coli (APC) Tumor-Suppressor Protein

Susan Munemitsu, Iris Albert, Brian Souza, Bonnee Rubinfeld and Paul Polakis

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.44 MB

english, 1995

38

Regulation of Epithelial Branching Morphogenesis and Cancer Cell Growth of the Prostate by Wnt Signaling

Wang, Bu-Er, Wang, Xi-De, Ernst, James A., Polakis, Paul, Gao, Wei-Qiang, Lopez-Schier, Hernan

Journal:

Year:

2008

Language:

english

File:

PDF, 1.45 MB

english, 2008

39

Stromal Cell-Derived Factor-1/CXCL12 Contributes to MMTV-Wnt1 Tumor Growth Involving Gr1+CD11b+ Cells

Liu, Bob Y., Soloviev, Irina, Chang, Peter, Lee, John, Huang, XiaoDong, Zhong, Cuiling, Ferrara, Napoleone, Polakis, Paul, Sakanaka, Chie, Blagosklonny, Mikhail V.

Journal:

Year:

2010

Language:

english

File:

PDF, 1.32 MB

english, 2010